Tissue Adhesive Cut Spine Surgery Closure Time
Patients undergoing spinal procedures may experience faster incision closing with tissue adhesive compared to traditional sutures.
Updated on Sept. 22, 2026 in Stroke

A clinical trial comparing topical tissue adhesive to subcuticular suturing for spinal surgery found that adhesive significantly reduced the time required to close incisions. The study involved 60 patients who each received both closure methods on bilateral incisions.
Why it matters
Reducing time in the operating room is a clinical priority that can streamline surgical workflows and potentially improve patient throughput. This trial offers evidence on how modern closure alternatives compare to the current standard of care regarding wound recovery.
This randomized trial of 60 patients compared two incision closure methods, showing tissue adhesive cut closure time by approximately half compared to sutures. Researchers found no statistically significant differences in objective scar outcomes at 12 months.
The details
In the trial, each of the 60 patients underwent minimally invasive spine surgery with bilateral incisions, with one side randomly assigned to topical tissue adhesive and the other to subcuticular suturing. Closure time for the adhesive averaged 171.1 seconds, whereas sutures required 347.5 seconds. Complication rates were low, with one case recorded for the adhesive group and zero for the suture group.
Timeline
Objective scar characteristics were assessed at 12 months.
Health Landscape
The use of the Vancouver scar scale as a benchmark for evaluating surgical healing outcomes provides a standardized, objective framework for comparing novel closure technologies against traditional suturing techniques. This study aligns with established research protocols by using such scales to provide an objective assessment of long-term healing.
If you are preparing for spinal surgery, you may want to ask your surgeon about the incision closure methods they use and whether they prioritize time-saving techniques. Discuss any history of difficult wound healing with your physician to understand which closure option is most appropriate for you.
The takeaway
While topical tissue adhesive significantly reduced surgery closure time compared to sutures, both methods showed comparable cosmetic results after one year. Always verify with your surgical team which method they plan to use and why it is the best fit for your specific procedure.
Further reading
Learn more about the latest innovations in surgical recovery and neurological care in our Stroke section.
Source note: This article includes information reported by Nature.







