OneSkin Released New Rich Moisturizer Formulation
The dermatologist-tested cream offers deeper hydration for those with dry or mature skin types.
Updated on Sept. 22, 2026 in Beauty
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OneSkin has released the OS-01 Face Rich Cream, a new moisturizer developed to provide intensive hydration. The product, which follows the company's original 2021 launch, is designed specifically for dry or mature skin.
Why it matters
This release provides a heavier moisturizing option for individuals managing hormonally depleted or chronically dry skin. The formula was developed over a two-year cycle to expand the brand's existing line of peptide-based skincare products.
A 12-week clinical study of 29 women assessed the efficacy of the new cream. Participants demonstrated a 38% increase in hydration and a 37% improvement in smoothness, though these findings are specific to this small cohort.
The players
OneSkin
A San Francisco-based biotechnology company that develops peptide-based skincare products.
The details
The formula utilizes a dual-phase system that pairs water-binding humectants with a triple-lipid barrier complex to support skin integrity. It incorporates the proprietary OS-01 peptide alongside ectoin, vegan collagen amino acids, tremella mushroom extract, and torula oil. The cream is non-comedogenic and holds the National Eczema Association Seal of Acceptance.
Timeline
OneSkin was founded by four scientists in 2016.
The company released its first moisturizer in 2021.
Researchers published data on the lead peptide candidate in 2023.
The OS-01 Face Rich Cream was released on September 22, 2026.
Health Landscape
This product release extends the application of the company's proprietary peptide research into the heavy-moisturizer market segment. It follows the established development trajectory of the company's OS-01 peptide research program.
If you have chronically dry or hormonally depleted skin, this cream may offer a useful barrier-supporting option to discuss with your dermatologist. It is worth noting that the product is non-comedogenic, making it suitable for those concerned about clogged pores while seeking intensive moisture.
The takeaway
The OS-01 Face Rich Cream utilizes a dual-phase system and a proprietary peptide to target hydration and smoothness. When introducing new topical products to your routine, consult your physician if you have a history of skin sensitivities or current dermatological conditions.
Further reading
For more on evolving standards in topical skin hydration, see Beauty.
More information
For more information on the product ingredients and development, visit the OneSkin product website.
Source note: This article includes information reported by Forbes.
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