Actor Josh Duhamel Shared Experience With Hormone Therapy
The 53-year-old actor discussed how he manages testosterone replacement therapy to support his energy levels.
Updated on Sept. 28, 2026 in Men’s Health
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Actor Josh Duhamel, who began testosterone replacement therapy in 2021, recently discussed his commitment to hormone optimization. He co-founded the health company Gatlan to offer resources to other men interested in similar medical guidance.
Why it matters
Managing hormone levels is a significant health decision for men, as FDA regulations mandate warnings for these products regarding potential increases in blood pressure. Men interested in hormone health should consult a physician to weigh the potential energy benefits against these established clinical risks.
This personal account involves a regimen of three weekly testosterone injections started in 2021 by a 53-year-old man. While individual outcomes vary, the FDA requires warnings for all testosterone products regarding potential effects on blood pressure.
The players
Josh Duhamel
An actor who has publicly shared his use of testosterone replacement therapy and co-founded a health company.
Gatlan
A men's health company that provides physician-guided information and services related to hormone optimization.
The details
Testosterone replacement therapy functions by supplementing the body with exogenous hormones to restore levels that may have declined. Gatlan provides a platform for men to access physician-guided care, which involves monitoring to achieve consistent hormone levels and mitigate potential side effects. Patients generally undergo clinical oversight to navigate the health risks, such as cardiovascular impacts, associated with hormone supplementation.
Timeline
Josh Duhamel initiated testosterone replacement therapy in 2021.
He and Audra Mari were married in September 2022.
The couple welcomed their son Shepherd in January 2024.
Their daughter, Rocca de Leon Duhamel, was born in May 2026.
This report was published on September 28, 2026.
Health Landscape
The use of testosterone replacement therapy falls under the safety framework defined by the FDA's warnings regarding potential blood pressure increases. This report reflects a broader trend of men seeking physician-guided hormone management as part of their aging and wellness strategy.
Men experiencing fatigue or other symptoms should discuss hormone screening with their primary care physician rather than self-initiating treatment. Because of the known risks associated with testosterone, it is essential to undergo professional monitoring to track blood pressure and other vital health markers.
The takeaway
Testosterone replacement is a medical intervention that requires ongoing supervision to manage potential side effects like elevated blood pressure. If you are considering hormone optimization, make an appointment with your doctor to review your current hormone panels and discuss the clinical safety profile.
Further reading
For more information on the risks and benefits of hormone health, visit our Men’s Health section.
Source note: This article includes information reported by Fox News.
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