Bipolar Research Network Has Opened New Site Applications
Healthcare organizations can now apply to join a network dedicated to improving care through longitudinal data collection.
Updated on Sept. 29, 2026 in Mental Health

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BD² has launched its third call for applications to expand its Integrated Network for bipolar disorder research. Public and private organizations in the U.S., Canada, and the U.K. can now compete for funding to join this international cohort study.
Why it matters
Expanding the network increases the scale of clinical data available to understand bipolar disorder, which may eventually lead to more personalized treatment pathways and improved patient outcomes.
The BD² Integrated Network previously released a longitudinal dataset from 615 participants in March 2026. This ongoing research effort seeks to collect data to characterize the disorder, though specific clinical conclusions from the cohort are still under investigation.
The players
BD²
A research organization dedicated to advancing the understanding and treatment of bipolar disorder through data-driven initiatives.
The details
Selected sites will receive up to $2.35 million USD in funding over five years to support their participation in the program. These institutions will contribute to both a Longitudinal Cohort Study and a Learning Health Network, which work together to track health outcomes and standard-of-care effectiveness across diverse clinical settings.
Timeline
March 2026: BD² released the initial dataset from 615 participants.
September 29, 2026: BD² announced its third call for applications.
January 15, 2027: The deadline for submitting application proposals.
May 2027: The date when selected awardees will be notified.
June 2027: The expected start date for the new clinical sites.
Health Landscape
The BD² Integrated Network expansion marks a transition from a pilot-scale data collection effort to a more expansive, international research framework. This initiative represents a departure from fragmented clinical record-keeping toward a unified, longitudinal model for bipolar disorder.
This development indicates that researchers are actively working to build a more robust evidence base for bipolar disorder treatments. If you are managing this condition, you may want to discuss the potential for future evidence-based care updates with your physician.
The takeaway
Large-scale longitudinal studies like the BD² Integrated Network are critical for uncovering patterns in bipolar disorder that single-clinic observations might miss. Patients can stay informed by following updates from major research cohorts to see how new clinical data shapes future guidelines.
What happens next
Organizations interested in participating must submit their proposals by January 15, 2027, with final awardees expected to be notified by May 2027.
Further reading
For more on ongoing advancements in psychiatric care, visit the Mental Health section of our site.
More information
Review the full application criteria and requirements on the BD² RFA Opportunities page.
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